Seong Jin Yu


Selective Publications

  1. Tsai-Wei Hung1, Kuo-Jen Wu1, Yu-Syuan Wang1, Eun-Kyung Bae1, YoungHa Song2, JongWon Yoon2, and Seong-Jin Yu1*.Human milk oligosaccharide 2′-fucosyllactose induces neuroprotection in intracerebral hemorrhage stroke brain, IJMS, 2021 In press
  2. Chen, YH;Wu, KJ;Hsieh, W;Harvey, BK;Hoffer, BJ;Wang, Y;Yu, SJ. Administration of AAV-Alpha Synuclein NAC Antibody Improves Locomotor Behavior in Rats Overexpressing Alpha Synuclein. 2021 Jun 21;12(6):Article number 948.
  3. Wang, YS;Hung, TW;Bae, EK;Wu, KJ;Hsieh, W;Yu, SJ. Naltrexone is neuroprotective against traumatic brain injury in mu opioid receptor knockout mice. CNS Neuroscience & Therapeutics. 2021;27:831–841.
  4. Yu, SJ;Wu, KJ;Wang, YS;Song, JS;Wu, CH;Jan, JJ;Bae, E;Chen, H;Shia, KS;Wang, Y. Protective effect of CXCR4 antagonist CX807 in a rat model of hemorrhagic stroke. International Journal of Molecular Sciences. 2020 Sep 25;21(19):Article number 7085.
  5. Yu, SJ;Chen, S;Yang, YY;Glotfelty, EJ;Jung, J;Kim, HK;Choi, HI;Choi, DS;Hoffer, BJ;Greig, NH;Wang, Y. PT320, sustained-release exendin-4, mitigates L-DOPA-Induced dyskinesia in a rat 6-Hydroxydopamine model of Parkinson’s disease. Frontiers in Neuroscience. 2020 Aug 11;14:Article number 785.
  6. Chen YH, Yu SJ, Wu KJ, Wang YS, Tsai HM, Liao LW, Chen SC, Hsieh W, Hsu SC, Chen ML, Hoffer BJ and Wang Y. Downregulation of a-Synuclein protein levels by an intracellular single-chain antibody. Journal of Parkinson’s disease. 2020 Mar 11;10(2):573-590.
  7. Yu SJ, Wu KJ, Bae EK, Wang YS, Chiang CW, Kuo LW, Harvey BK, Greig NH, Wang Y. Post-treatment with Posiphen reduces endoplasmic reticulum stress and neurodegeneration in stroke brain. iScience. 2020 Feb 21;23(2):Article number 100866.
  8. Wu KJ, Chen YH, Bae EK, Song Y, Min W, Yu SJ* (Correspondence). Human Milk Oligosaccharide 2′-Fucosyllactose Reduces Neurodegeneration in Stroke Brain. Transl Stroke Res. 2020 [Epub ahead of print] 
  9. Kaneko Y, Lee JY, Tajiri N, Tuazon JP, Lippert T, Russo E, Yu SJ, Bonsack B, Coats AB, Kingsbury C, Chase TN, Koqa M, Borlongan CV. Translating intracarotid artery transplantation of bone marrow-derived NCS-01 cells for ischemic stroke: behavioral and histological readouts and mechanistic insights into stem cell therapy. Stem Cells Transl Med. 2019 Nov 18. doi: 10.1002/sctm.19-0229. [Epub ahead of print]
  10. Sheyner M, Yu SJ, Wang Y. Enhanced survival of human-induced pluripotent stem cell transplant in parkinsonian rat brain by locally applied cyclosporine. Brain Circ. 2019 Sep 30;5(3):130-133.
  11. Zhang Y, Yu S, Tuazon JP, Lee JY, Corey S, Kvederis L, Kingsbury C, Kaneko Y, Borlongan CV, Neuroprotective effects of human bone marrow mesenchymal stem cells against cerebral ischemia are mediated in part by an anti-apoptotic mechanism. Neural Regen Res. 2019; 14(4):597-604
  12. Chen S, Yu SJ, Li Y, Lecca D, Glotfelty E, Choi HI, Hoffer BJ, Greig NH, Kim DS, Wang Y, Post-treatment with PT302, a Long-acting Exendin-4 Sustained Release Formulation, Reduces Neurodegeneration of Dopaminergic Neurons in a 6-Hydroxydopamine Rat Model of Parkinson’s DiseaseSci Rep.2018; 8(1):10722. 
  13. Wu KJ, Yu SJ, Chiang CW, Lee YW, Yen BL, Tseng PC, Kuo LW, Wang Y, Neuroprotective action of human Wharton’s Jelly derived-mesenchymal stromal cell transplants in a rodent model of stroke, Cell Transplant. 2018; 27(1): 096368971880275 [Epub ahead of print]
  14. Wu KJ, Yu SJ, Chiang CW, Lee YW, Yen BL, Hsu CS, Kuo LW, Wang Y. Wharton’ jelly mesenchymal stromal cell therapy for ischemic brain injury. Brain Circ. 2018; 4(3):124-127.
  15. Wu KJ, Yu SJ, Lee JY, Hoffer B, Wang Y. Improving neurorepair in stroke brain through endogenous neurogenesis-enhancing drugs.Cell Transplant. 2017;26(9):1596-1600. 
  16. Dewan SN, Wang Y, Yu SJ*. Drug treatments that optimize endogenous neurogenesis as a therapeutic option for stroke. Brain Circulation. 2017;3(3):152-155. 
  17. Yu SJ, Airavaara M, Wu KJ, Harvey BK, Liu HS, Yang Y, Zacharek A, Chen J, Wang Y. 9-cis retinoic acid induces neurorepair in stroke brain. Sci Rep. 2017; 7(1):4512.
  18. Wu K, Yu SJ, Shia K, Wu C, Song J, Kuan H, Yeh K, Chen C, Bae E, Wang Y. A novel CXCR4 antagonist CX549 induces neuroprotection in stroke brain. Cell Transplant. 2017;26(4):571-583. 
  19. Li Y, Wu KJ, Yu SJ, Tamargo IA, Wang Y, Greig NH. Neurotrophic and neuroprotective effects of oxyntomodulin in neuronal cells and a rat model of stroke. Exp Neurol. 2017; 288:104-113. 
  20. Tamargo IA, Bader M, Li Y, Yu SJ, Wang Y, Talbot K, DiMarchi RD, Pick CG, Greig NH. Novel GLP-1R/GIPR co-agonist “twincretin” is neuroprotective in cell and rodent models of mild traumatic brain injury. Exp Neurol. 2017; 288:176-186. 
  21. Yu SJ, Wu KJ, Bae EK, Hsu MJ, Richie CT, Harvey BK, Wang Y. Methamphetamine induces a rapid increase of intracellular Ca(++) levels in neurons overexpressing GCaMP5. Addict Biol. 2016;21:255-266. 
  22. Kuo CC, Shen H, Harvey BK, Yu SJ, Kopajtic T, Hinkle JJ, Kyrkanides S, Katz JL, Wang Y. Differential modulation of methamphetamine-mediated behavioral sensitization by overexpression of Mu opioid receptors in nucleus accumbens and ventral tegmental area. Psychopharmacology (Berl). 2016 Feb;233(4):661-72. 
  23. Yu SJ, Reiner D, Shen H, Wu KJ, Liu QR, Wang Y. Time-Dependent Protection of CB2 Receptor Agonist in Stroke. PLoS One. 2015;10(7): e0132487 
  24. Wu KJ, Yu SJ, Chiang CW, Cho KH, Lee YW, Yen BL, Kuo LW, Wang Y. Transplantation of human placenta-derived multipotent stem cells reduces ischemic brain injury in adult rats. Cell Transplant. 2015; 24:459-470.
  25. Reiner DJ, Yu SJ, Shen H, He Y, Bae EK, Wang Y. 9‐Cis retinoic acid protects against Methamphetamine‐induced neurotoxicity in nigrostriatal dopamine neurons. Neurotox Res. 2014; 25:248‐261. 

Last Update: 2021-09-13

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