【2023 學術演講】Biofluid Markers of Parkinson’s Disease

2023 神醫中心學術演講  (實體) 

日期 : 2月 22日星期二

時間 : 上午11:00  

地點 : 國衛院竹南院區/ 行政大樓B1第4會議室

主題 : Biofluid Markers of Parkinson’s Disease

講師 : Chin-Hsien Lin (林靜嫻), MD. Ph.D.

臺大醫院臨床神經暨行為醫學中心主任

臺大醫院神經部主治醫師暨臨床教授

報名連結



摘要

Parkinson’s disease (PD) is a common neurodegenerative disease featuring
progressive decline of both motor and non-motor functions. Cognitive decline is one
of the most frequent and disabling non-motor symptoms. Given the likely entry of
several classes of mechanism-targeted therapies into early human clinical trials, the
identification of easily accessible biomarkers that could reflect disease severity in PD
is urgently needed. In this speech, I am going to update the recent advances in the
development of blood-based PD biomarkers from different aspects, including
variable forms of a-synuclein, tau, neurofilament light chain and the gut metabolites.
Although various biomarkers for PD have been developed so far, their specificity and
sensitivity are not ideal when applied individually. So, the combination of multimodal
biomarkers will greatly improve the diagnostic accuracy, assist the differential
diagnosis with various Parkinsonian syndromes and facilitate the implementation of
personalized medicine.


會後合照


更新 : 2023-01-17

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