【學術演講】 Towards clinical translation of next-generation stroke management

2021 神醫中心學術演講 (現場+視訊) 

日期 : 12月 28日星期二

時間 : 上午11:00  

地點 : 國衛院竹南院區/ 行政大樓B1第6會議室 

主題 :  Towards clinical translation of next-generation stroke management

講師 : 李怡慧 主任/ 教授

          台北榮民總醫院神經內科腦血管科主任

          國立陽明大學腦科學研究所教授

報名連結


視訊系統 Webex  : 會議連結     密碼: 1234

摘要

This lecture will discuss the current state of endovascular thrombectomy in ischemic stroke and future directions in adjunctive treatment in the post-reperfusion era and pre-symptomatic intervention in high-risk subjects.  The issues around adjunctive neural stem cell-based therapy and pharmacological targets of neuroprotection for clinical trials will be discussed, particularly Nerinetide and aryl hydrocarbon receptor modulation. In post-acute patients, enhancement of neuroplasticity utilizing non-invasive transcranial brain stimulation will be outlined. We conducted a randomized controlled trial of bihemispheric tDCS during task-oriented training, which facilitated motor recovery in early subacute stroke patients. Next-generation sequencing technology has challenged pre-symptomatic risk prediction. We unravel a significant proportion of stroke-causing variants that might have been overlooked in a diverse spectrum of familial stroke phenotypes, particularly with small vessel disease, intracerebral hemorrhage and other undetermined infarction. The results reveal the characteristic genetic epidemiology in Taiwan and support the feasibility of advanced genetic diagnosis of well-characterized familial stroke.


2021-12-15

 


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