Pao-Luh Tao


Pao-Luh Tao, Ph.D.
Visiting Professor
Extension: 36708
E-mail: pltao@nhri.org.tw

 


Education

1988/03 – 1991/07 Ph.D., Department of Pharmacology, University of Minnesota, U.S.A.
1972/07 – 1974/08 M.S., Graduate Institute of Biophisics, National Defense Medical Center, Taiwan
1968/07 – 1972/06 B.S., Department of Pharmacy, College of Medicine, National Taiwan University, Taiwan

Positions

2015-present Visiting Professor; Center for Neuropsychiatric Research, National Health Research Institutes, Taiwan, ROC.
2012/09 – Investigator, Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Miaoli County,Taiwan,ROC
2010/08 – 2012/08 Investigator, Division of Mental Health and Addiction Medicine, Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Miaoli County,Taiwan,ROC
1999/03 – 2005/04 Chairman, Depatment of Pharmacology, National Defense Medical Center, Taipei,Taiwan,ROC
1991/08 – 2010/07 Professor, Depatment of Pharmacology, National Defense Medical Center, Taipei,Taiwan,ROC
1985/07 – 1991/07 Associate Professor, Depatment of Pharmacology, National Defense Medical Center, Taipei,Taiwan,ROC
1979/08 – 1985/06 Instructor, Depatment of Pharmacology, National Defense Medical Center, Taipei,Taiwan,ROC
1974/08 – 1979/07 Associate Investigator, Medical Research Department, Tri-service General Hospital, Taipei,Taiwan,ROC

Expertise

  • Opioid Pharmacology
  • Drug addiction

Honors & Awards

2009 Awards for Excellent Teachers (National Defense Medical Center, Taiwan/R.O.C.)
2008 Awards for Excellent Teachers (National Defense Medical Center, Taiwan/R.O.C.)
2006 Awards for Excellent Teachers (National Defense Medical Center, Taiwan/R.O.C.)
2004 Awards for Excellent Scientific Articles (elected by the National Defense Medical Center, Taiwan/R.O.C.)
2004 Awards for the Research of Program Project at National Health Research Institutes
2001 Awards for Excellent Teachers (National Defense Medical Center, Taiwan/R.O.C.)
1999 Awards for Excellent Scientific Articles (elected by the National Defense Medical Center, Taiwan/R.O.C.)
1990 Awards for Excellent Scientific Articles (elected by the National Defense Medical Center, Taiwan/R.O.C.)
1984-1990 Research Awards from National Science Council

Selective Publications

  1. Tao PL*, 2016, Reply to: Agonism at delta-opioid receptor contributes to the antinociceptive effect of oxycodone in mice. Pharmacological Research 114: 293.
  2. Yang PP, Yeh GC, Yeh TK, Xi J, Loh HH, Law PY, Tao PL*, 2016, Activation of delta-opioid receptor contributes to the antinociceptive effect of oxycodone in mice. Pharmacological Research 111 (2016) 867–876.
  3. Shen YL, Chen ST, Chan TY, Hung TW, Tao PL, Liao RM, Chan H, Chen HH*, 2016, Delayed extinction and stronger rug-primed reinstatement of methamphetamine seeking in rats prenatally exposed to morphine. Neurobiology of Learning and Memory 128:56–64
  4. Yang PP, Yeh GC, Huang E YK, Law PY, Loh HH., Tao PL*, 2015, Effects of dextromethorphan and oxycodone on treatment of neuropathic pain in mice. Journal of Biomedical Science 2015, 22:81. doi:10.1186/s12929-015-0186-3
  5. Chiang Y-C, Ye L-C, Hsu K-Y, Liao C-W, Hung T-W, Lo W-J, Ho I-K, Tao PL*, 2015, Benefit effects of co-treatment with dextromethorphan on prenatally methadone-exposed offspring. Journal of Biomedical Science 22:19 
  6. Kao J-H, Gao M-J, Yang P-P, Law P-Y, Loh H H, Tao PL*, 2014, The effect of naltrexone on neuropathic pain in mice locally transfected with the mutant mu-opioid receptor gene in spinal cord. Br. J. Pharmacol. doi: 10.1111/bph.12790. [Epub ahead of print] PMID: 24866991 [PubMed – as supplied by publisher]. (SCI).
  7. Yang CP, Cherng CH, Wu CT, Huang HY, Tao PL, Lee SO, Wong CS*. Intrathecal ultra-low dose naloxone enhances the antihyperalgesic effects of morphine and attenuates tumor necrosis factor-α and tumor necrosis factor-α receptor 1 expression in the dorsal horn of rats with partial sciatic nerve transection. Anesth Analg. 2013 Dec; 117(6):1493-502. (SCI)
  8. Chow L-H, Tao P-LChen J-C, Liao R-M, Chang E-P, Huang, E Y-K*, 2013, A possible correlation between oxytocin-induced and angiotensin IV-induced anti-hyperalgesia at the spinal level in rats, Peptides 39: 21-28. (SCI)
  9. Wang K-C, Lee Y-J, Fan L-W, Yang P-P, Tao P-L, Ho I-K, Tien L-T*, 2013, Mu-opioid receptor knockout mice are more sensitive to chlordiazepoxide-induced anxiolytic behavior, Brain Research Bulletin 90:137– 141. (SCI)
  10. Cai B-H, Hsu P-C, Hsin I-L, Chao C-F, Lu M-H, Lin H-C, Chiou S-H, Tao P-L, Chen J-Y*, 2012, p53 Acts as a Co-Repressor to Regulate Keratin 14 Expression during Epidermal Cell Differentiation. PLoS ONE 7(7): e41742. doi:10.1371/journal.pone.0041742 (SCI)
  11. Chen S-L, Lee S-Y, Tao P-L, Chang Y-H, Chen S-H, Chu C-H, Chen PS, Lee IH, Yeh TL, Yang YK, Hong J-S, Lu R-B*, 2012, Dextromethorphan Attenuated Inflammation and Combined Opioid Use in Humans Undergoing Methadone Maintenance Treatment, J Neuroimmune Pharmacol 7:1025-33. (SCI)
  12. Yang PP,Huang E Y-K, FuYY, Ho TS, Tao P-L*, 2012, Post-treatment of dextromethorphan on methamphetamine-induced drug-seeking and behavioral sensitization in rats, Synapse 66:858–869. (SCI)
  13. Cheng BC, Tao PL, Cheng YY, Huang EY*, 2012, LVV-hemorphin 7 and angiotensin IV in correlation with antinociception and anti-thermal hyperalgesia in rats, Peptides: 36:9-16 (SCI).
  14. Chen S-L, Tao P-L, Chu C-H, Chen S-H, Wu H-E, Tseng LF, Hong J-S, Lu R-B*, 2012,Low-dose memantine attenuated morphine addictive behavior through its anti-inflammation and neurotrophic effects in rats, J. Neuroimmune Pharmacol. 7:444-453 (SCI).
  15. Chou SH, Kao JH, Tao P-L*Law PY  and Loh HH, 2012, Naloxone can act as an analgesic agent without measurable chronic side effects in mice with a mutant mu-opioid receptor expressed in different sites of pain pathway, Synapse 66:694-704 (March, 2012). (SCI).
  16. Yang CP, Cherng CH, Wu CT, Huang HY, Tao PL, Wong CS*, 2011, Intrathecal ultra-low dose naloxone enhances the antinociceptive effect of morphine by enhancing the reuptake of excitatory amino acids from the synaptic cleft in the spinal cord of partial sciatic nerve-transected rats, Anesth Analg. 113:1490-1500 (SCI).
  17. Tao P-LHuang E Y-K *, 2011, J. Biomed. Sci. 18: 64 (23 August 2011). (SCI).
  18. Kao J. H., Huang E Y-K, Tao P-L*, 2011, NR2B subunit of NMDA receptor at nucleus accumbens is involved in morphine rewarding effect by siRNA study, Drug and Alcohol Dependence 118: 366-374. (SCI).
  19. Chen, S-L, Hsu K-Y, Huang E Y-K, Lu R-BTao P-L*, 2011, Low doses of dextromethorphan attenuate morphine-induced rewarding via the sigma-1 receptor at ventral tegmental area in rats, Drug and Alcohol Dependence 117: 164–169. (SCI).
  20. Chen JY-R, Yeh G-C, Tao P-L, Kuo C-T, Chen K-B, Wen Y-R,2010, Prenatal exposure to methamphetamine alters the mechanical withdrawal threshold and tonic hyperalgesia in the offspring, Neurotoxicology 31: 432-438. (SCI).
  21. Wu C-H, Tao P-L, and Huang, E.Y.-K.,2010, Distribution of neuropeptide FF (NPFF) receptors in correlation with morphine-induced reward in the rat brain. Peptides 31:1374-1382. (SCI).

Last Update: 2018-05-25

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